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Description

Abstract: Reusing clinical data from electronic health records and linking with registry and research omics data would provide a wealth of information for clinical audits and translational research to improve patient care and support precision medicine. The challenge is ensuring high data quality, automation and suitable analytics and governance. We developed a data warehouse for a number of clinical areas that has successfully been utilised to inform on outcomes and support biomarker studies in renal transplantation.

Learning Objective 1: Health informaticians, clinical researchers, system developers, investigators and learners interested in health data governance would gain insight from our experience of developing an informatics and governance approach to support translational research in one of the largest biomedical research centres in the U.K. It includes the challenges of re-using and linking EHR, registry and omics data for research purposes, the developed solutions, and illustration of the capability with clinically-led analysis and findings from renal transplantation audits and biomarker studies.

Authors:

Anastassia Spiridou (Presenter)
NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust & King's College London

the NIHR Health Informatics Collaborative NIHR HIC, National Institute of Health Research
Syed Hasan, Guy's and St Thomas' NHS Foundation Trust
Bolaji Coker, Guy's and St Thomas' NHS Foundation Trust
Stevo Durbaba, King's College London
Jonathan Smith, King's College London
S G, Guy's and St Thomas' NHS Foundation Trust
Florence Delaney, Guy's and St Thomas' NHS Foundation Trust
Sofia Christakoudi, King's College London
Rosa Montero, Guy's and St Thomas' NHS Foundation Trust
Elham Asgari, Guy's and St Thomas' NHS Foundation Trust
Rute Aguiar, Guy's and St Thomas' NHS Foundation Trust
Paramit Chowdhury, Guy's and St Thomas' NHS Foundation Trust
Maria Hernandez Fuentes, King's College London

Presentation Materials:

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